Benign Prostatic Hyperplasia
What is BPH? What are the causes?
BPH is an acronym for Benign Prostatic Hyperplasia (or prostatic adenoma). It is a disease characterized by increased prostate gland volume, mainly due to an increase in the number of cells in the gland itself.
The aetiology of BPH is not yet known precisely. However, some of the factors associated with the onset of the disease are known: the main ones are aging and hormonal changes occurring in advanced age. In particular, it seems that dihydrotestosterone (DHT), a male sex hormone that stimulates cell growth in prostate tissue, plays a crucial role in enlarging the gland; Moreover, oestrogen may be implicated in the onset of the disorder, since BPH is most frequently diagnosed in men with high levels of oestrogen and low levels of free testosterone.